自Premack首次分享他的想法以来，与人和动物的多次研究都支持以他的名字命名的原理。 最早的研究之一是Premack本人进行的。 Premack首先确定他的幼儿参与者是否喜欢打弹球或吃糖果。 然后，他在两种情况下对它们进行了测试：一种情况是孩子必须吃弹球才能吃糖果，而另一种情况下孩子必须吃糖才能弹球。 Premack发现，在每种情况下，只有喜欢序列中第二行为的孩子才会表现出增强作用，这是Premack原理的证据。 艾伦（Allen）和岩田ata（Iwata）在后来的一项研究中证明，在玩游戏（一种高频率的行为）时，一群发育障碍的人的锻炼取决于运动（一种低频率的行为）。
Since Premack first shared his ideas, many studies with humans and animals have supported the principles of his name. One of the earliest studies was conducted by Premack himself. Premack first determines if his toddler participant likes to play pinball or eat candy. He then tested them in two situations: one in which the child had to eat a pinball to eat candy, and the other in which the child had to eat sugar to play the ball. Premack found that in each case, only children who like the second behavior in the sequence showed an enhancement, which is evidence of the Premack principle. In a later study, Allen and Iwata proved that when playing games (a high-frequency behavior), the exercise of a group of people with developmental disabilities depends on exercise (a low-frequency behavior). ).